Sanakirja
Tekoälykääntäjä
Kuvat 5

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Määritelmät

Substantiivi

  1. (organic chemistry) MPP+, the active metabolite of MPTP.
  2. (neurotoxicology) A neurotoxin that cannot cross the blood-brain barrier but which, once in contact, can destroy the dopaminergic neurons of the substantia nigra.

Esimerkit

  • Apical uptake was higher than basolateral uptake at 37 degrees C and was decreased to 70% in the presence of NaN(3) or in the absence of extracellular Na(+). Besides alpha2-agonists, apical uptake was inhibited by verapamil, desipramine, and quinidine, but not by MPP(+) (1-methyl-4-phenylpyridinium), TEA (tetraethylammonium), decynium-22, carnitine, PHA (p-aminohippurate), alanine, or inosine.

(organic chemistry) MPP+, the active metabolite of MPTP.

MPP+; 1-methyl-4-phenylpyridinium

(organic chemistry) MPP+, the active metabolite of MPTP.

Ball-and-stick model of the 1-methyl-4-phenylpyridinium cation, also known as MPP+ (with a positive charge of 1), a neurotoxin used as a herbicide. Color code:   Carbon, C: black   Hydrogen, H: white   Nitrogen, N: blue

(organic chemistry) MPP+, the active metabolite of MPTP.

Reaction scheme for the laboratory synthesis of MPP+.