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haematopoiesis

Diagram showing the development of different blood cells from haematopoietic stem cell to mature cells

haematopoiesis

Sites of haematopoiesis (human) in pre- and postnatal periods

haematopoiesis

More detailed and comprehensive diagram that shows the development of different blood cells in humans:

• The morphological characteristics of the hematopoietic cells are shown as seen in a Wright's stain, May-Giemsa stain or May-Grünwald-Giemsa stain. Alternative names of certain cells are indicated between parentheses.
• Certain cells may have more than one characteristic appearance. In these cases, more than one representation of the same cell has been included.
• Together, the monocyte and the lymphocytes comprise the agranulocytes, as opposed to the granulocytes (basophil, neutrophil and eosinophil) that are produced during granulopoiesis.
• B., N. and E. stand for Basophilic, Neutrophilic and Eosinophilic, respectively – as in Basophilic promyelocyte. For lymphocytes, the T and B are actual designations.

1. The polychromatic erythrocyte (reticulocyte) at the right shows its characteristic appearance when stained with methylene blue or Azure B.
2. The erythrocyte at the right is a more accurate representation of its appearance in reality when viewed through a microscope.
3. Other cells that arise from the monocyte: osteoclast, microglia (central nervous system), Langerhans cell (epidermis), Kupffer cell (liver).
4. For clarity, the T and B lymphocyte are split to better indicate that the plasma cell arises from the B-cell. Note that there is no difference in the appearance of B- and T-cells unless specific staining is applied.