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• On the other hand, adult respiratory distress syndrome is a prominent complication in patients with acute leukaemia and to this must be added the whole spectrum of opportunistic infections.
• The molecular biologists′ vision that the cloning of the chromosomal translocations found in human leukaemias would lead to the identification of the genes that cause these leukaemias has become a reality with the demonstration that the fusion protein generated by the chromosomal translocation found in chronic myelogenous leukaemia (CML) can induce leukaemia in mice (Daley et al, 1990; Kelliher et al, 1990).
• In transmitted mouse leukaemia the cells remain fixed in type, but tissue culture methods applied to human acute leukaemias show that these cells are not fixed in type.
• There are different types of childhood leukaemia, which can be classified as acute or chronic. In children, about 98 per cent of leukaemias are acute.