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| Monikko | neprilysins |
(biochemistry) A particular type of metalloprotease, namely membrane metallo-endopeptidase (MME)
The structure of neprilysin, a zinc metalloprotease involved in the metabolism of extracellular regulatory peptides such as the enkephalins and substance P. Neprilysin in neural tissue is the major protease degrading amyloid beta, a peptide fragment whose abnormal misfolding and aggregation is associated with Alzheimer's disease. The gray sphere represents a zinc atom; the green structure is a zinc-chelating enzyme inhibitor.
(biochemistry) A particular type of metalloprotease, namely membrane metallo-endopeptidase (MME)
Neprilysin immunohistochemical staining of normal kidney.