A large settlement, bigger than a town; sometimes with a specific legal definition, depending on the place.
(UK, historical in Ireland and Commonwealth) A settlement granted special status by royal charter or letters patent; traditionally, a settlement with a cathedral regardless of size.
(slang) A large amount of something (used after the noun).
Esimerkit
São Paulo is one of the largest cities in South America.
So this was my future home, I thought![...]Backed by towering hills, the but faintly discernible purple line of the French boundary off to the southwest, a sky of palest Gobelin flecked with fat, fleecy little clouds, it in truth looked a dear little city; the city of one's dreams.
One of the hidden glories of Victorian engineering is proper drains. Isolating a city’s effluent and shipping it away in underground sewers has probably saved more lives than any medical procedure except vaccination.
I'm going into the city today to do some shopping.