Sanakirja
Tekoälykääntäjä
| Kieli | Käännökset |
|---|---|
| italia | esaltatore |
| ranska | amplificateur, exhausteur |
| suomi | voimistaja |
| venäjä | усилитель (usilitel) |
Määritelmät
Substantiivi
- Something that enhances.
- (genetics) A short region of DNA that can increase transcription of genes
Esimerkit
- Mucuna pruriens' Latin name may be thought to suggest its predilection, but actually means itchy. Nonetheless, one can easily find it being sold in capsules as a sex enhancer. It has actually been used as such in Ayurvedic medicine for centuries.
Taivutusmuodot
| Monikko | enhancers |
Luokat
(genetics) A short region of DNA that can increase transcription of genes
Extremely idealized enhancer with no mention of chromatin
(genetics) A short region of DNA that can increase transcription of genes
Seen here is a four step diagram depicting the usage of an enhancer. Within this DNA sequence, protein(s) known as transcription factor(s) bind to the enhancer and increase the activity of the promoter.
- DNA
- Enhancer
- Promoter
- Gene
- Transcription Activator Protein
- Mediator Protein
- RNA Polymerase
(genetics) A short region of DNA that can increase transcription of genes
Regulation of transcription in mammals. An active enhancer regulatory region of DNA is enabled to interact with the promoter DNA region of its target gene by the formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the gene. The loop is stabilized by one architectural protein anchored to the enhancer and one anchored to the promoter and these proteins are joined to form a dimer (red zigzags). Specific regulatory transcription factors bind to DNA sequence motifs on the enhancer. General transcription factors bind to the promoter. When a transcription factor is activated by a signal (here indicated as phosphorylation shown by a small red star on a transcription factor on the enhancer) the enhancer is activated and can now activate its target promoter. The active enhancer is transcribed on each strand of DNA in opposite directions by bound RNAP IIs. Mediator (a complex consisting of about 26 proteins in an interacting structure) communicates regulatory signals from the enhancer DNA-bound transcription factors to the promoter.