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(biochemistry) molecules that bind to enzymes and decrease their activity

Top: enzyme (E) accelerates conversion of substrates (S) to products (P). Bottom: by binding to the enzyme, inhibitor (I) blocks binding of substrate. Binding site shown in blue checkerboard, substrate as black rectangle, and inhibitor as green rounded rectangle.

(biochemistry) molecules that bind to enzymes and decrease their activity

The coenzyme folic acid (top) compared to the anti-cancer drug methotrexate (bottom)