| Kieli | Käännökset |
|---|---|
| ranska | mutation non-sens |
| suomi | nonsense-mutaatio |
| Monikko | nonsense mutations |
(genetics) A point mutation that generates either a premature stop codon, or a codon that does not specify any amino acid.
Pictured on the left is a diagram of normal translation occurring without mutation. Blue circles are the peptides already translated while the grey circles are peptides going to be translated next. In the center is a diagram a nonsense mutation where the UUG codon is translated to the stop codon UAG. The stop codon recruits a release factor, terminating translation. On the right is a diagram of the tRNA suppression mechanism where the codon and the tRNA are both mutated, resulting in tRNA suppression. The mutated Tyr tRNA has the anticodon AUC which recognizes the UAG stop codon, continuing protein translation.
(genetics) A point mutation that generates either a premature stop codon, or a codon that does not specify any amino acid.
Selection of notable mutations, ordered in a standard table of the genetic code of amino acids. nonsense mutations are marked by red arrows.